IN SITU TRANSPLANTATION OF ADIPOSE-DERIVED STEM CELLS VIA PHOTOACTIVATION IMPROVES GLUCOSE METABOLISM IN OBESE MICE

In situ transplantation of adipose-derived stem cells via photoactivation improves glucose metabolism in obese mice

Abstract Background Accumulating evidence suggests that enhanced adipose tissue Backpacks macrophages (ATMs) are associated with metabolic disorders in obesity and type 2 diabetes.However, therapeutic persistence and reduced homing stem cell function following cell delivery remains a critical hurdle for the clinical translation of stem cells in cur

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Effects of ultrasonic impact treatment on surface residual stress and electrochemical properties of 42CrMo4 steel

ObjectiveThe effects of different ultrasonic impact treatment time on cross section microstructure, surface residual stress, surface microhardness, and corrosion Rompers resistance of 42CrMo4 steel sample was investigated.ResultsThe results showed that after ultrasonic impact, a large amount of plastic deformation occurred on the surface of 42CrMo4

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The transcriptomic response of cells to a drug combination is more than the sum of the responses to the monotherapies

Our ability to discover effective drug combinations is limited, in part by insufficient understanding of how the transcriptional response of two monotherapies results in that of their combination.We analyzed matched time course RNAseq profiling of cells treated with single drugs and their combinations and found Backpacks that the transcriptional si

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